Full time
Pfizer
Groton, CT
Job Description & Responsibilities Pfizer is seeking a highly motivated Postdoctoral Fellow with training in structural biology of G protein‑coupled receptors (GPCRs) or other membrane proteins to advance next‑generation structure‑based drug discovery (SBDD) by integrating pharmacology, cryo‑electron microscopy (cryo‑EM), and artificial intelligence (AI)–enabled experimental strategies to interrogate dynamic and pharmacologically relevant GPCR functional states. This role is part of an R&D‑funded, AI‑focused postdoctoral initiative aimed at enabling structural access to GPCR conformations that are currently difficult or impossible to study using conventional approaches. The successful candidate will work at the interface of experimental GPCR pharmacology and high‑resolution cryo-EM structural biology and will have a unique opportunity to collaborate closely with a parallel AI/ML/Computer Science–focused postdoctoral fellow, contributing experimental data and domain...

