Broad Institute

General information Location Cambridge, MA Ref # 44040 Job Family Research Workplace On-Site Date published 04/23/2026 Time Type Full time Pay Range $70,000.00/yr - $92,666.67/yr Description & Requirements The Zhang lab at The Broad Institute of MIT & Harvard is seeking an exceptional scientist to join our mission of discovering and developing new molecular biology tools to improve human health for their postdoctoral training. The Zhang lab has pioneered the development of a number of new biotechnologies, including CRISPR-mediated genome editing, new approaches for high-throughput genetic screening, DNA microscopy, CRISPR-based diagnostics, and single-cell genomics methods. These advancements often stem from natural systems, and the lab is also at the forefront of discovering and characterizing novel molecular systems. Collectively, our work encompasses many disciplines, including computational biology,...

General information Location Cambridge, MA Ref # 44033 Job Family Research Workplace On-Site Date published 04/21/2026 Time Type Full time Pay Range $58,000.00/yr - $80,667.00/yr Description & Requirements About the Broad The Broad Institute of MIT and Harvard is the world’s leading biomedical research institute dedicated to the bold mission of using the full power of genomics to transform the understanding and treatment of disease. The Broad Institute seeks to describe all of the molecular components of life and their connections; discover the molecular basis of major human diseases; develop effective new approaches to diagnostics and therapeutics; and disseminate discoveries, tools, methods, and data openly to the entire scientific community. Founded in 2004, the Broad Institute includes faculty, professional staff, and students from throughout the MIT and Harvard biomedical research communities and...

General information Location Cambridge, MA Ref # 44072 Job Family Research Workplace Remote Date published 04/23/2026 Time Type Full time Pay Range $70,500.00/yr - $99,750.00/yr Description & Requirements The Scalable Services Group at the Broad Institute of MIT & Harvard is seeking a Product Manager II to lead the development of platforms and applications that power both the generation and the effective use of some of the largest genomic datasets in the world. In addition to building scalable systems for data production, this role will drive the creation of intuitive, researcher-facing tools that enable scientists to explore, analyze, and derive insight from complex genomic and multi-omic data. This includes work supporting major national efforts such as the All of Us Research Program, helping democratize access to high-quality biomedical data and empowering a diverse research community. Your work...

General information Location Cambridge, MA Ref # 44075 Job Family Research Date published 04/23/2026 Time Type Full time Pay Range $88,000.00/yr - $124,000.00/yr Description & Requirements The Somatic Mosaicism across Human Tissues (SMaHT) Network was established by the NIH to catalog somatic genetic variation across human tissues and discover its patterns, causes and consequences. This effort includes all classes of somatic mutation: single nucleotide variants, short insertions and deletions, structural variants, and other large chromosomal aberrations. The somatic mutation catalog will enable downstream analyses, such as rates and burdens of mutations across tissues, mutational signature analysis, driver mutations and clonal expansions, and lineage tracing. The Broad Institute is one of five Genome Characterization Centers (GCCs) tasked with delivering the sequencing data underpinning this somatic mutation...

General information Location Cambridge, MA Ref # 44034 Job Family Research Date published 04/22/2026 Time Type Full time Pay Range $58,000.00/yr - $80,667.00/yr Description & Requirements The Broad Institute of MIT & Harvard, a world leader in genetic research, is looking for an exceptional candidate to join the Spatial Technology Platform (STP). STP utilizes cutting-edge spatial profiling methods to generate highly multiplexed and multi-modal data sets at single-cell resolution as a high-throughput scaled service at the Broad Institute. In addition, our platform develops and pilots new technologies and capabilities that have potential for scaled service implementation, including cross-modality assays and technologies at precommercial stages. Our focus lies in highly multiplexed spatial transcriptomics alongside in situ proteomics and optical barcoding technologies for demultiplexing CRISPR perturbations. Our...

General information Location Cambridge, MA Ref # 44028 Job Family Research Workplace On-Site Date published 04/21/2026 Time Type Full time Pay Range $70,000.00/yr - $92,666.67/yr Description & Requirements The Hwang laboratory at the Broad Institute of MIT & Harvard is seeking a highly motivated postdoctoral associate to investigate the mechanisms of organ dysfunction and immune paralysis in sepsis using clinical samples and animal models. Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Despite considerable advances over the last decades, sepsis is still a leading cause of death in intensive care units, and survivors develop prolonged immune paralysis leading to a high incidence of recurrent infections. In the absence of definitive therapy, physicians rely on supportive care. Our team is devoted to deep understanding of immune dysfunction in...

General information Location Cambridge, MA Ref # 44000 Job Family Administration Workplace On-Site Date published 04/14/2026 Time Type Full time Pay Range $162,000.00/yr - $226,000.00/yr Description & Requirements The Broad Institute of MIT and Harvard is seeking a Director of Research Operations to lead global research programs at the intersection of mental health, psychiatric epidemiology, and human genetics. This role will drive the strategy, execution, and continuous improvement of complex, multi-site studies conducted across the United States, Africa, Latin America, and other international settings. The Director will oversee day-to-day and long-term research operations, including study implementation, data and biospecimen workflows, regulatory compliance, and financial management. They will design and scale operational infrastructure to support high-quality, ethical research across diverse global...

General information Location Cambridge, MA Ref # 44026 Job Family Research Workplace On-Site Date published 04/13/2026 Time Type Full time Pay Range $58,000.00/yr - $80,667.00/yr Description & Requirements The Vector Engineering laboratory led by Ben Deverman is looking for a research associate to join our team. We are a fast-paced and mission-driven collaborative laboratory focused on developing next-generation adeno-associated viral (AAV) vectors for neuroscience research and for CNS gene therapies. In this role, you will assist with the execution of in vitro and in vivo studies aimed at developing a brain-wide gene therapy for a genetically defined neurodegenerative disease. For examples of our recent work, please see the references at the end of the job description. Success in this role will require that you are meticulous with your lab work and documentation, and that you are able to work closely with...

General information Location Cambridge, MA Ref # 44017 Job Family Administration Date published 04/10/2026 Time Type Full time Pay Range $27.88/hr - $36.86/hr Description & Requirements Ops Specialist I - Uhler Lab The Ops Specialist I provides administrative and operational support to the Uhler Lab and the Eric and Wendy Schmidt Center. This role performs a range of administrative tasks following established procedures and guidelines. The Ops Specialist I responds to routine inquiries and assists with coordination of meetings, travel, and lab activities while developing familiarity with departmental processes and systems. Key Responsibilities Provide administrative support to Professor Caroline Uhler and the Uhler Lab by assisting with scheduling, coordination, and routine operational tasks. Assist with maintaining Prof. Uhler’s calendar by scheduling meetings and coordinating logistics for lab...

General information Location Cambridge, MA Ref # 43998 Job Family Research Workplace On-Site Date published 04/10/2026 Time Type Full time Pay Range $58,000.00/yr - $80,667.00/yr Description & Requirements Embedded within the Broad Institute, the Center for the Development of Therapeutics (CDoT) is a highly collaborative organization of professional drug discovery scientists. Our mission is to translate cutting-edge biological insights originating from the Broad community into impactful drug discovery projects. We partner with faculty from MIT, Harvard, and the Harvard teaching hospitals, along with industry partners in pharmaceutical, biotechnology and venture capital firms to validate druggable targets and identify leads. We combine our deep expertise in drug discovery with the knowledge and unique capabilities of the Broad Institute to address a wide range of disease areas (including oncology,...

General information Location Cambridge, MA Ref # 43957 Job Family Research Date published 04/09/2026 Time Type Full time Pay Range $88,000.00/yr - $124,000.00/yr Description & Requirements Embedded within the Broad Institute of Harvard and MIT, the Center for the Development of Therapeutics (CDoT) is a highly collaborative organization of professional drug discovery scientists. Our mission is to translate the deep biological insights emerging from the Broad community into new therapeutics. To accomplish this mission, we partner with faculty from MIT, Harvard, and the Harvard teaching hospitals together with industry professionals in pharmaceutical, biotechnology and venture capital firms and advance cutting-edge drug discovery projects. We create new technologies and work to apply the unique capabilities of the Broad Institute to enable new therapeutic approaches that will broadly benefit the scientific community....

General information Location Cambridge, MA Ref # 43959 Job Family Research Workplace On-Site Date published 04/07/2026 Time Type Full time Pay Range $70,000.00/yr - $92,666.67/yr Description & Requirements Overview: The Getz Lab (at the Broad Institute and MGH) is a world-leading laboratory for cancer genome analysis. We develop highly innovative, robust, and widely-used computational methods to study the molecular basis of cancer, including genomic alterations that drive primary and resistant tumors, cell-of-origin, premalignant lesions, mutational processes, activity of different pathways, and microenvironmental changes. We then follow up key findings experimentally. While the comprehensive analysis of cancer genomes is ongoing, major barriers still exist in converting this information to patient benefit and achieving the goal of personalized medicine. Our work stands at the forefront of cancer genome...

General information Location Cambridge, MA Ref # 43997 Job Family Research Workplace On-Site Date published 04/06/2026 Time Type Full time Pay Range $100,000.00/yr - $140,000.00/yr Description & Requirements The Broad Institute of MIT and Harvard is one of the world's leading biomedical research institutes. It seeks to discover the molecular basis of major human diseases, develop effective new approaches to diagnostics and therapeutics, and disseminate discoveries, tools, methods, and data openly to the entire scientific community. Founded in 2004, the Broad Institute includes faculty, professional staff, and students from throughout the MIT and Harvard biomedical research communities, with collaborations spanning the globe. The Macosko Lab, within the Broad Institute of MIT & Harvard, is seeking a highly skilled and innovative Neuroscientist to lead the application of our pioneering spatial profiling...

General information Location Cambridge, MA Ref # 43962 Job Family Research Date published 04/02/2026 Time Type Full time Pay Range $88,000.00/yr - $124,000.00/yr Description & Requirements The Broad Institute of MIT and Harvard is a leading biomedical research institute dedicated to the bold mission of using the full power of genomics to transform the understanding and treatment of disease. The Broad Institute seeks to describe all of the molecular components of life and their connections; discover the molecular basis of major human diseases; develop effective new approaches to diagnostics and therapeutics; and disseminate discoveries, tools, methods, and data openly to the entire scientific community. Founded in 2004 by Eric Lander and philanthropists Eli and Edythe L. Broad, the Broad Institute ncludes faculty, professional staff, and students from throughout the MIT and Harvard biomedical research communities...

General information Location Cambridge, MA Ref # 43925 Job Family Research Date published 03/27/2026 Time Type Full time Pay Range $58,000.00/yr - $80,667.00/yr Description & Requirements The Stevens lab is looking for a motivated and energetic Research Associate to join the neurobiology group at the Stanley Center for Psychiatric Research. This is an exciting opportunity to support and collaboratively develop new research into neuroimmune interactions, brain development, and genetic risk factors for schizophrenia, Alzheimer’s disease, and other neurological disorders. The Stevens lab uses animal and cell culture model systems to understand the development and functions of diverse brain cell types, synapses and circuits. The lab collaborates widely across the neurobiology, genetics and therapeutics divisions of the Stanley Center, and with platforms, programs, and investigators throughout the Broad, Boston...