Feb 06, 2026

Engineer

Job Description

Job Title: Senior AI Fullstack Engineer

Long term contract

South San Franscisco, CA ONSITE C2C

Description:

Job Title: Senior AI Fullstack Engineer

The Position

We advance science so that we all have more time with the people we love. Genentech s Early Clinical Development (ECD) department is seeking a talented and motivated Software Developer reporting to the Director of software engineering at The Clinical Data Insights & Automation team (CDI&A). The CDI&A team collaborates with a broad range of stakeholders involved in the clinical development process (e.g., Clinical Science, Clinical Operations, Medical Writing, Quality, Regulatory). It develops industry- leading solutions for highly complex business problems. To manage the design and pilot of these software products, they apply a high degree of ingenuity and creativity while maintaining a finger on the pulses of the rapidly changing tech and healthcare landscapes.

The Software Engineer will primarily be responsible for designing, developing, and deploying software which interacts with cutting-edge generative AI models and applications in collaboration with AI scientists, full stack developers, and others. Their work will directly impact our ability to create and deliver innovative solutions that leverage AI to solve complex problems and enhance user experiences.

The Opportunity:

  • Innovate and develop software applications to support clinical development
  • Identify and integrate AI/LLM capabilities to enhance data processing and natural workflows.
  • Design intuitive, user-centric interfaces.

Code Quality and Documentation:

  • Write clean, maintainable, and well- documented code.
  • Participate in code reviews and contribute to best practices in software development.

Research and Innovation:

  • Stay up-to-date with the latest advancements in generative AI and machine learning.
  • Evaluate new technologies and methodologies to continuously improve our solutions.

Collaborate with Cross-Functional Teams:

  • Work closely with data scientists, engineers, and product managers to integrate generative AI capabilities into our products and services.

Deployment and Monitoring:

  • Develop and maintain robust deployment pipelines for AI-enhanced applications.
  • Monitor pipeline performance in production and implement necessary improvements.

Who You Are:

An experienced full stack developer capable of bringing your expertise to our existing and upcoming AI applications/projects as both a leader and individual contributor. Someone with a clear understanding of the current landscape of AI & AI-based applications, including potential benefits, limitations, and standard of practice.

Minimum Requirements:

  • Bachelor s or Master s degree in Computer Science, Engineering, Mathematics, or a related field.
  • 5+ years of full stack development experience (Overall 10+ yrs of IT Experience)
  • Strong proficiency in either a front-end framework (Vue.js, React, or similar) and a backend web frameworks in Python and/or JavaScript (Django, FastAPI, Flask, Next.js, or similar)
  • 4+ years experience with front-end frameworks (preferably Vue.js)
  • 2+ years of developing and deploying AI/ML solutions or applications
  • Experience designing and developing RESTful APIs (with e.g. Python FastAPI).
  • Familiarity with prompt engineering
  • Proficiency with containerized workflows and architectures (Podman, Docker, Kubernetes)
  • Strong automated software testing skills (Python unittest, jest, Playwright)
  • Familiar with Agile methodologies
  • Excellent analytical and problem-solving skills with a track record of tackling complex technical challenges.
  • Leading system design and implementing scalable, fault-tolerant solutions for complex, distributed computing challenges.
  • Strong interpersonal and communication skills, with the ability to articulate complex technical concepts to non-technical stakeholders.
  • Experience with cloud platforms (e.g. AWS) and modern data platforms (e.g., Snowflake).
  • Experience implementing chatbots, retrieval-augmented generation (RAG) systems, and integrating LLMs into applications (AI-assisted automation)

Preferred Qualifications:

  • Experience building AI agents, fine-tuning LLM models, and evaluating bias and fairness with LLM systems
  • Experience in developing Microsoft Word add-ins using Office.js.
  • Experience with web technologies like JWT, WebSockets, etc.
  • Experience with Huggingface, Langchain, TensorFlow, PyTorch, or similar.
  • Familiarity with DevOps, infrastructure, and continuous integration concepts.
  • Familiarity with CRDT technologies like Yjs.
  • Experience with using NLP/LLMs on clinical text.
  • Basic knowledge of clinical drug development

Note for Vendors for sourcing: Kindly look for profiles - Senior AI Fullstack Engineer role focused on building production-grade AI/LLM-powered applications for Genentech s clinical development teams. The candidate must be a senior full-stack engineer with 5+ years of experience, strong Python backend (FastAPI/Flask/Django) and frontend framework experience (Vue.js preferred). Mandatory 2+ years of hands-on AI/ML application development, including LLM integration, prompt engineering, chatbots, and RAG systems. Experience deploying applications using Docker, Kubernetes, and AWS is required. The role involves designing scalable, fault-tolerant systems, strong testing practices, and working in Agile, regulated environments. Strong communication skills and ability to collaborate with clinical and non-technical stakeholders are essential.

For applications and inquiries, contact: hirings@openkyber.com