Postdoctoral Research Fellow

Site: The Brigham and Women's Hospital, Inc.

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

We are seeking a highly motivated postdoctoral fellow to join the Korecka Lab. The position will focus on two interconnected research areas: (1) elucidating the cellular mechanisms underlying epilepsy in dentatorubral–pallidoluysian atrophy (DRPLA) and evaluating gene therapy–based rescue strategies, and (2) defining the role of neuroinflammation in disease progression across rare genetic ataxias.

The Korecka Lab investigates early disruptions in neuronal activity that drive neurodegenerative phenotypes. We study how these changes arise from intrinsic genetic dysfunction as well as extrinsic influences, including microbiome alterations and neuroimmune signaling. Using patient-derived iPSC models combined with advanced live-cell functional assays, our goal is to uncover disease mechanisms and accelerate the development of next-generation antisense and gene-modifying therapies.

We are looking for candidates with prior experience in iPSC culture and differentiation, strong data analysis skills, and an interest in computational approaches. Ideal candidates are collaborative, highly motivated, and passionate about neuroscience, with a keen interest in neuronal function, electrophysiology, and cellular systems.”

Candidates should have a Ph.D.

PhD degree Required

If interested in applying, please send resume and cover letter to Joanna Korecka-Roet, jkorecka-roet@bwh.harvard.edu

Onsite

60 Fenwood Road

2200 The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

Mass General Brigham Competency Framework