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28 principal scientist jobs found in Cambridge

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Cambridge United States principal scientist
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BM
Principal Scientist Computational Biology
BristolMyers Squibb Cambridge, MA, USA
Working with Us Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us . Job Description We seek a creative and passionate computational...

Feb 17, 2026
BM
Full time
 
Principal Scientist, In Vivo Pharmacology, Oncology Discovery Biology
Bristol Myers Squibb Careers Cambridge, MA, USA
Working with Us Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more careers.bms.com/working-with-us . The Oncology Thematic Research Center at BMS is a key research and early...

Feb 16, 2026
MI
Full time
 
Principal Scientist, T Cell Immunology (Autoimmunity and Infectious Disease)
Moderna, Inc. Cambridge, MA, USA
The Role Moderna is seeking a talented, experienced, and motivated candidate to lead innovative immunology efforts across autoimmune and infectious disease programs. This role will drive mechanistic discovery and translational immunology to enable antigen-specific and pathway-directed mRNA-LNP therapeutics. The ideal candidate brings deep expertise in T cell biology in the setting of autoimmunity and/or infectious diseases, a strong track record of scientific leadership, and the ability to collaborate effectively across multi-disciplinary teams. Here’s What You’ll Do Lead preclinical research efforts in one or more autoimmune or infectious disease programs from early discovery through IND-enabling studies. Establish preclinical models and perform T cell immune profiling to support target discovery, validation and clinical enablement. Drive translational research to elucidate therapeutic mechanism of action through analysis of human clinical samples. Contribute to...

Feb 13, 2026
MI
Full time
 
Principal Scientist, T Cell Immunology (Autoimmunity and Infectious Disease)
Moderna, Inc. Cambridge, MA, USA
The Role: Moderna is seeking a talented, experienced, and motivated candidate to lead innovative immunology efforts across autoimmune and infectious disease programs. This role will drive mechanistic discovery and translational immunology to enable antigen-specific and pathway-directed mRNA-LNP therapeutics. The ideal candidate brings deep expertise in T cell biology in the setting of autoimmunity and/or infectious diseases, a strong track record of scientific leadership, and the ability to collaborate effectively across multi-disciplinary teams. Here’s What You’ll Do: Lead preclinical research efforts in one or more autoimmune or infectious disease programs from early discovery through IND-enabling studies. Establish preclinical models and perform T cell immune profiling to support target discovery, validation and clinical enablement. Drive translational research to elucidate therapeutic mechanism of action through analysis of human clinical samples....

Feb 13, 2026
BI
Full time
 
Research Scientist I - The Zhang Lab
Broad Institute Cambridge, MA, USA
General information Location Cambridge, MA Ref # 43643 Job Family Research Workplace On-Site Date published 02/20/2026 Time Type Full time Pay Range $88,000.00/yr - $124,000.00/yr Description & Requirements The Zhang Lab explores and studies biological diversity to understand nature and discover systems and processes that may be harnessed through bioengineering for the improvement of human well-being. We are looking to recruit a sharp, experienced, creative, and independent scientist to lead a project focused on therapeutic cellular engineering. The candidate will pursue his/her own project within the group, collaborating with existing lab members or new hires as needed to advance the project. The Zhang lab is a member of the Broad Institute of MIT & Harvard and McGovern Institute at MIT, and a part of the greater Boston life-science community including MIT and Harvard. Our lab is a fun, fast-paced,...

Feb 23, 2026
HC
Full time
 
Director of Business Development
Harvard Central Administration (CADM) Talent Acquisition Cambridge, MA, USA
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise. We are dedicated to creating a diverse and welcoming environment where everyone can thrive. About the Harvard Office of Technology Development (OTD) The Office of Technology Development (OTD) is part of Harvard University's Central Administration. OTD fulfills the University's commitment to translate technologies developed in Harvard labs for the public good and to establish corporate partnerships that advance research towards commercial impact. Job Description Reporting to the Associate Provost and Chief Technology Development Officer, the Director of Business Development (DBD) will support OTD's core mission to 1) commercialize technologies emerging from Harvard labs and 2) secure funding from corporate...

Feb 21, 2026
SI
Full time
 
IT Specialist (APPSW), (IS-2210-11/12)
Smithsonian Institution Cambridge, MA, USA
Description OPENING DATE: February 17, 2026 CLOSING DATE: February 22, 2026 TYPE OF POSITION: Trust Indefinite (Non-Federal) DIVISION: Business Operations LOCATION: Cambridge, MA AREA OF CONSIDERATION: This position is open to all eligible candidates. This is a career ladder opportunity with promotion potential to grade 12. Selection will be made at grade level 11. The candidate may be non-competitively promoted to the next higher grade level, up to grade 12, upon the supervisor's recommendation, based on classification requirements, satisfactory performance, and the employee's qualifications. What are Trust Fund Positions? Trust Fund positions are unique to the Smithsonian. They are paid for from a variety of sources, including the Smithsonian endowment, revenue from our business activities, donations, grants and contracts. Trust employees are not part of the civil service, nor does trust fund employment lead to Federal status. The salary ranges...

Feb 20, 2026
HC
Full time
 
Director of Business Development
Harvard Central Administration (CADM) Talent Acquisition Cambridge, MA, USA
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise. We are dedicated to creating a diverse and welcoming environment where everyone can thrive. About The Harvard Office Of Technology Development (OTD) The Office of Technology Development (OTD) is part of Harvard University's Central Administration. OTD fulfills the University’s commitment to translate technologies developed in Harvard labs for the public good and to establish corporate partnerships that advance research towards commercial impact. Job Description Reporting to the Associate Provost and Chief Technology Development Officer, the Director of Business Development (DBD) will support OTD’s core mission to 1) commercialize technologies emerging from Harvard labs and 2) secure funding from corporate sources to advance research. The DBD will be...

Feb 20, 2026
Draper
Full time
 
Principal Avionics Electrical Engineer
Draper Cambridge, MA, USA
Posted today Public Trust $95,000 - $237,500 Unspecified Engineering - Electrical Cambridge, MA (On-Site/Office) Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com . Job Description Summary: We are seeking a Principal Electrical Engineer to support our growing demand for the design of avionics solutions across numerous programs. This position will require extensive knowledge and experience designing...

Feb 19, 2026
Draper
Full time
 
Principal Avionics Electrical Engineer
Draper Cambridge, MA, USA
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com. Job Description Summary: We are seeking a Principal Electrical Engineer to support our growing demand for the design of avionics solutions across numerous programs. This position will require extensive knowledge and experience designing complex electronic solutions that are integrated into large-scale systems. The engineer develops the architecture, designs circuits, performs simulations,...

Feb 19, 2026
Draper
Full time
 
Principal Power Electronics Engineer
Draper Cambridge, MA, USA
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com. Job Description Summary: A Principal Power Electronics Engineer designs, specifies, develops, and tests power system architectures and requirements for a wide array of applications, including miniature power conversion and management circuitry, distributed power architectures, radiation hardened designs, novel battery management circuitry, small motor controllers, switched-mode power conversion...

Feb 15, 2026
Draper
Full time
 
Principal Power Electronics Engineer
Draper Cambridge, MA, USA
Overview Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com. Job Description Summary A Principal Power Electronics Engineer designs, specifies, develops, and tests power system architectures and requirements for a wide array of applications, including miniature power conversion and management circuitry, distributed power architectures, radiation hardened designs, novel battery management circuitry, small motor controllers, switched-mode power conversion and...

Feb 15, 2026
HU
Postdoctoral Researcher Position in Active & Soft Condensed Matter Theory at Harvard University
Harvard University Cambridge, MA, USA
Details Title Postdoctoral Researcher Position in Active & Soft Condensed Matter Theory at Harvard University School Faculty of Arts and Sciences Department/Area Physics Position Description Postdoctoral Researcher Position in Active & Soft Condensed Matter Theory at Harvard University The Soft Condensed Matter and Active Matter Theory groups in the Department of Physics at Harvard University, led by Professors David Nelson and Sunghan Ro, expect to appoint one postdoctoral fellow beginning in Fall 2026. We seek candidates with interests in soft condensed matter theory, including (but not limited to) population dynamics, hydrodynamics, elastic structures, active matter, and nonequilibrium statistical physics. Applicants should arrange for letters of recommendation from at least three scientists familiar with their work. Applicants must submit a cover letter including a brief description of past research and future research interests, and may also submit...

Feb 14, 2026
Draper
Full time
 
Principal Program Finance Analyst
Draper Cambridge, MA, USA
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com. Job Description Summary: The Program Finance Analyst, Principal will report to the Director of Program Finance. This role requires an ability to think independently, strategically and tactically to drive transformation, efficiency, and compliance in the area of Earned Value Management and Program Controls This role is designed to design and implement core program control procedures and tools...

Feb 12, 2026
Draper
Full time
 
Group Lead-Production Design, Verification & Validation
Draper Cambridge, MA, USA
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com. Job Description Summary: The Production, Mission, Operations, & Enhancements Division within the Systems Engineering directorate is seeking a Group Leader to lead our Production Design, Verification & Validation. The Division serves as the system integrator for technologies and product lines developed using Draper's core capabilities. The Division plans, executes, and manages...

Feb 07, 2026
Draper
Full time
 
Principal DevSecOps Engineer
Draper Cambridge, MA, USA
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com. Job Description Summary: The Principal DevSecOps Modernization Lead is a technical and organizational leader responsible for setting vision, strategy, and execution for modern, secure software delivery practices across a large, multi-team program. This role provides strategic technical direction, drives consensus across diverse stakeholders, and leads change for the program. Core elements of...

Feb 07, 2026
Draper
Full time
 
Principal Hardware Integration and Test Engineer
Draper Cambridge, MA, USA
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com. Job Description Summary: The Aiding Technologies Integration & Test Group at Draper is seeking a Principal Integration & Test Engineer with broad technical skills and a wealth of industry experience to lead/advise teams in a multidisciplinary environment to conceptualize, build, and test advanced electro-mechanical and electro-optical systems for a wide range of applications including...

Feb 07, 2026
Draper
Full time
 
Principal Electrical Engineer
Draper Cambridge, MA, USA
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com. Job Description Summary: We are seeking a Principal Electrical Engineer to support our growing demand for the design of avionics solutions across numerous programs. This position will require extensive knowledge and experience designing complex electronic solutions that are integrated into large-scale systems. The engineer develops the architecture, designs circuits, performs simulations,...

Feb 07, 2026
Draper
Full time
 
Principal Sensor Systems Engineer
Draper Cambridge, MA, USA
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com. Job Description Summary: The Inertial Sensor Integration & Test Group at Draper is seeking a principal engineer with broad technical skills to work in a multidisciplinary environment to conceptualize, develop, analyze, and assess robust GN&C (Guidance, Navigation and Control) sensors and systems for a wide variety of applications, including defense systems. Program roles will usually be...

Feb 07, 2026
Draper
Full time
 
Principal Acoustic System Architect
Draper Cambridge, MA, USA
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com. Job Description Summary: Draper's Acoustic and Vibration Technologies group is seeking a Principal Acoustic System Architect to lead the development of novel transducer technology, from initial concept through design and delivery. You will directly contribute to and/or oversee a diverse set of tasks including mechanical design, transducer modeling and control, system architecture, materials...

Feb 07, 2026
Draper
Full time
 
Principal LabVIEW Test Equipment Development Engineer
Draper Cambridge, MA, USA
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com. Job Description Summary: The Test Equipment Development group within the Production, Mission, Operations and Enhancements division at Draper is seeking a Principal LabVIEW Test Equipment Development Engineer to lead multidisciplinary strategic systems test equipment development, providing full system lifecycle development and management of complex electrical, mechanical and software-based test...

Feb 07, 2026
Draper
Full time
 
Principal Integration and Test Systems Engineer
Draper Cambridge, MA, USA
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com. Job Description Summary: The Sensors Integration & Test Group at Draper is seeking a principal engineer with a broad technical skills to work in a multidisciplinary environment to conceptualize, develop, analyze, and assess robust GN&C (Guidance, Navigation and Control) sensors and systems for a wide variety of applications, including defense systems. Program roles will usually be...

Feb 07, 2026
Draper
Full time
 
Principal system architect
Draper Cambridge, MA, USA
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com. Job Description Summary: Draper's Acoustic and Vibration Technologies group is seeking a Principal Acoustic System Architect to lead the development of novel transducer technology, from initial concept through design and delivery. You will directly contribute to and/or oversee a diverse set of tasks including mechanical design, transducer modeling and control, system architecture, materials...

Feb 07, 2026
Draper
Full time
 
Principal Cable and Harness DfX Engineer
Draper Cambridge, MA, USA
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com. Job Description Summary: Draper is seeking a Design for Manufacturing/Assembly engineer with experience in cable and harness design and fabrication. The Principal Cable and Harness DFX Engineer works with the design and production teams, as well as Supply Chain, to ensure Design for Manufacturing/Assembly principles are applied and works towards a smooth transition to internal or external...

Feb 06, 2026
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